It is the sodium salt of benzoic acid and exists in this form when dissolved in water. It is widely used in low pH foods and drinks and it is GRAS, Generally Recognized as Safe. A male workmate and I were discussing food the other day and the types of food we have been told for 40 plus years to eat instead of the foods we probably grew up on. Potassium sorbate is a popular food additive. APPARENTLY SAFE. Also, according to a recent report, the U.S. ranks 8th for cancer in women and 10th in the world for cancers in men. Sodium benzoate is a chemical used as a preservative in for several types of food, including margarine, soft drinks, pickles, jelly and jam. In the United States, sodium benzoate is designated as generally recognized as safe (GRAS) by the Food and Drug Administration. Sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. Dangerous food preservatives, colors, flavors' enhancers numbers of other additives to stop including in our daily diet. [8] Tuesday, 23 April 2013. Sodium benzoate ph range. Yes, because is produced by reacting sodium hydroxide with benzoic acid. There is mild concern that sodium benzoate may be linked to cancer, as it can break down into benzene – a known carcinogen. What is E211? The food additive 211 is a common preservative that the FDA finds safe for human consumption. This led up to the 1906 Pure Food and Drug Act, a landmark event in the early history of food regulation in the United States. Other sources include seafood, such as prawns, and dairy products like milk, cheese, and yogurt. [10][11] This leads to excretion of these amino acids and a decrease in ammonia levels. (2). Sodium benzoate, utilized as a food additive in a variety of processed food products and drinks, is capable of reacting with added vitamin C to form benzene, which acts as a carcinogen. Dried tree fruit such as apricots, peaches, apples and pears are mostly sulphited unless from specialty stores (see dangers of dried fruit factsheet) Dates, prunes, figs, sultanas and raisins may be sulphite-free but can contain extra high levels of salicylates. Sodium benzoate has been replaced by potassium sorbate in the majority of soft drinks in the United Kingdom.[9]. It is also used as a preservative in medicines and cosmetics. It is especially used to preserve acidic foods and beverages such as pickles, salad dressings, fruit juices, and soft drinks. Typically, artificial colors are chemical-based dyes that are used to color food and drinks. He concluded that the sodium benzoate in the soft drinks sampled actually caused damage to the mitochondria, which plays a critical role in the generation of metabolic energy in a eukaryotic cell. Sodium benzoate (E211) is a salt derived from benzoic acid, used as a preservative in a variety of foods, beverages, condiments and cosmetics (mouthwash, shampoo, body lotions, and deodorant). 211 Sodium benzoate, preservative. [27] Heat, light and shelf life can increase the rate at which benzene is formed. MSG flavor information also under … They are also considered dangerous for asthmatics and people sensitive to Asprin (salicylates). Hey, Nabende Sudi. Lastly, people who have experienced benzene poisoning needing medical treatment show a notable risk of mortality from leukemia. . To begin, the sodium benzoate preservative controversy started in 2005 when some soft drinks tested positive for carcinogenic benzene. Am B+ blood group i eat ovacado any harm? It is most widely used in acidic foods such as salad dressings (i.e. Citric acid 330 - e330 fully explained. In 2011, scientists at the Department of Biology, Gazi University, Ankara, Turkey, evaluated the genotoxic impact of this substance in cultured human cells. Sodium benzoate is a preservative added to some sodas, packaged foods, and personal care products to prolong shelf life. Has natural occurrence in several fruits. Your Health Remedy is a website for those who aspire to improve themselves and their life, as well as contribute to making the world a better place to live. Concentration as a food preservative is limited by the Food and Drug Administration in the United States to 0.1 percent by weight. Sodium Benzoate (E211) is a preservative used to prevent food from molding. For instance, according to In 2011, the CDC,  the percentage of children in the US who have ever been diagnosed with this condition is now 9.5 percent. We will discuss the possible side effects of potassium sorbate in this NutriNeat article. 2. Studies have shown that Red Dye No. Artificial food additives numbers and codes, their list can be printed out. Allergies occur when the immune system reacts to a foreign substance, like – bee venom, pollen, or pet dander as well as a food which doesn’t cause a reaction in the majority of people. 100 - 182. Sodium Benzoate is dangerous when combined with ascorbic acid. Sodium Stearoyl Lactylate (E481) - Uses and Adverse Effects, Arnuity Ellipta vs Flovent For Asthma – Differences & Side Effects, 25 Interesting Facts About Angelman Syndrome And Its Symptoms, Causes + Statistics, Interesting Facts About Meningitis And Its Symptoms, Causes, Prevention, 21 Interesting Facts About Gonorrhea + Symptoms, Causes, Prevention. [21] The International Programme on Chemical Safety found no adverse effects in humans at doses of 647–825 mg/kg of body weight per day. Yes. Sulfites. Even the most dedicated of us can get fed up trying to make sense of what is (and isn’t) on the labels. Sodium benzoate common name: E211, sodium salt of benzoic acid, benzoate of soda, food preservative 211, class 2 preservatives ins 211, e 211 preservative, ins 211 preservative. Natural alternatives to this compound do exist. But what exactly is E211? Also in milk and meat products, relishes and condiments, baked goods and lollies. The best PH value is 2.5 ~ 4.0. There are many chemical additives that present health hazards, but synthetic E211 is particularly dangerous because it is able to damage parts of the DNA. Four had benzene levels that were above the 5 ppb Maximum Contaminant Level set by the Environmental Protection Agency for drinking water. The concern over artificial colours was fuelled by a UK government-funded study in 2010, which concluded that a mixture of colourings and the preservative sodium benzoate (211) could be linked to increased hyperactivity in some children. by up to 5 points in children. Sodium Benzoate is a preservative most widely used in acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments. Sodium benzoate (E211) is a salt derived from benzoic acid, used as a preservative in a variety of foods, beverages, condiments and cosmetics (mouthwash, shampoo, body lotions, and deodorant). These researchers tested preservatives that are often used in nasal drops, eyedrops and cosmetics on rats and concluded that even a low-concentration solution of preservatives can lead to nasal lesions. However, because of questionable benefit and transient action, most authorities believe caffeine and other analeptics should not be used in these conditions and recommend other supportive therapy. Many other influences are at work but this at least is one a child can avoid. Symptoms usually appear within minutes to several hours after ingesting foods containing this compound. Benzoic acid, its salts like sodium benzoate and its esters are found in many natural food sources. Benzoates (210 - 213) - The preservative benzoate is found in soft drinks and particularly cordials. Orange soft drinks contain a high amount of it, upto 25mg per 250ml. AVOID IF POSSIBLE. Sodium benzoate E211 is not recommended as a food preservative at pH ranges higher than 4.5. These compounds are usually used to preserve dry fruits, canned fruits, corn syrup, pepper, … [4] Fruits and vegetables can be rich sources, particularly berries such as cranberry and bilberry. In May 2007, professor Peter Piper, an expert on aging, molecular biology and biotechnology at the University of Sheffield, conducted a test on living yeast cells in his lab. The chemical could be harmful to cats if they consume products with this preservative. The use of preservatives sodium benzoate (E211) and potassium benzoate (E212) in food products containing vitamin c causes the formation of highly dangerous carcinogen benzene, when injected daily could trigger the formation of cancer or aids the growth of malignant tumor cells. [5][6] Under these conditions it is converted into benzoic acid (E210), which is bacteriostatic and fungistatic. [15][16], Sodium benzoate, along with caffeine, is used to treat postdural puncture headache, respiratory depression associated with overdosage of narcotics,[17][18] and with ergotamine to treat vascular headache.[19]. Concentration as a food preservative is limited by the FDA in the U.S. to 0.1% by weight. Benzoates, also known as flowers of benzoin, phenlycarboxylic acid, benzene carboxylic … 100, 101, 103, 106, 140, 141, 160 160a, 161, 161a-f, 161h, 162, 163, 170, 181. [24], The human body rapidly clears sodium benzoate by combining it with glycine to form hippuric acid which is then excreted. This means that the E211 consumed today may still be causing problems for future generations. Caffeine and Sodium Benzoate Injection (caffeine alkaloid) is used along with supportive measure to treat respiratory depression associated with over dosage with CNS depressant drugs, such as narcotics. They tested reactions to a mixture of six colours and the preservative sodium benzoate (211), a preservative found in many lollies and soft drinks. All rights reserved. Sustained and excessive consumption of artificial preservatives can weaken heart tissues which is dangerous especially for the aged people. [22][23], Cats have a significantly lower tolerance against benzoic acid and its salts than rats and mice. It is most widely used in acidic foods such as salad dressings (i.e. Sodium benzoate (also shown as 211 on labels) is a preservative used in many foods and beverages and can be difficult to avoid. Sodium benzoate is a preservative, with the E number E211. Concentration used is 0.1% w/w or less. Don’t consume it, the body will take care of the rest. Benzoic acid is generally not used directly due to its poor water solubility. In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate may form benzene. It is also used as a preservative in medicines and cosmetics. These preservatives do a good job of protecting the multidose bottle of medication, but they have the potential for long-term deleterious effects on the eye. Yellow No. In 2006, the Food and Drug Administration tested 100 beverages available in the United States that contained both ascorbic acid and benzoate. It is a widely used food pickling agent, with an E number of E211. Although non-toxic and safe for use, some of its properties may not be favorable for health. 102,104, 105, 107. Also, it is the main ingredient of various paint stripper products, spot removers, and rubber cement, due to its highly solvent and destructive qualities. . Most processed foods, candies, beverages and many condiments contain artificial coloring.There is great concern that artificial food coloring may cause increased hyperactivity in children.1. Being an artificial preservative, sustained and excessive consumption of this preservative can weaken heart tissues which is dangerous especially for the aged people. In combination with ascorbic acid (vitamin C, E300), potassium benzoate and E211 may form benzene, a known carcinogen and DNA damager. Benzoates. Under these conditions it is converted into benzoic acid (E210), which is bacteriostatic and fungistatic. This Buzzle article further lays out the health dangers of this chemical preservative. Research published in 2007 for the UK's Food Standards Agency (FSA) suggests that certain artificial colors, when paired with sodium benzoate, may be linked to hyperactive behavior. acetic acid in vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (acetic acid), condiments, and frozen yogurt toppings. A few animal reproduction studies have established an adverse effect on the fetus. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. The backstory of sodium benzoate used as a preservative Soft drink survey. Schizophrenia is a severe mental disorder which affects how a person feels, thinks, and behaves. Sodium benzoate is the sodium salt of benzoic acid and is commonly used as an antimicrobial substance and food preservative. [23] The metabolic pathway for this begins with the conversion of benzoate by butyrate-CoA ligase into an intermediate product, benzoyl-CoA,[25] which is then metabolized by glycine N-acyltransferase into hippuric acid.[26]. An allergy to sodium benzoate (211) can be a challenging allergy to manage. Sodium benzoate is produced by the neutralization of benzoic acid,[3] which is itself produced commercially by partial oxidation of toluene with oxygen. Long-term use of preservatives on rat nasal respiratory mucosa: effects of benzalkonium chloride and potassium sorbate, 2000;110(2 Pt 1):312-7. So there’s a good and bad side to preservatives—especially the older, soap-like preservatives in the quaternary ammonium family of chemicals, which include benzalkonium chloride, or BAK. The mechanism starts with the absorption of benzoic acid into the cell. Sodium benzoate is a widely used food preservative, with an E number of E211.It can be produced by reacting benzoic acid with sodium hydroxide. This is the identification of sodium benzoate. 3. Factors such as heat and time can affect their development. Researchers at Southampton University noted that tests have shown that this chemical lowers the I.Q. E211 is used to help inhibit the growth of fungus and bacteria in acidic products. They also concluded that artificial colors or E211 preservatives (or both) in the diet result in increased hyperactivity in 3-year-old and 8/9-year-old children in the general population. Sodium benzoate is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited. Colours. Some people claim that this man-made additive is … In addition, men have a higher chance of developing cancer than women. No. Webster's dictionary describes the uses of this substance as: "antiseptic, as a food preservative, and to disguise taste, as of poor-quality food". „These chemicals have the ability to cause severe damage to DNA in the mitochondria to the point that they totally inactivate it: they knock it out altogether” – Professor Peter Piper. (1). The fungicide and insecticide substance found naturally in avocados (persin) may damage the DNA of normal cells, as well as cancer cells. According to a 2018 randomized, double-blind, placebo-controlled trial which was led by Dr Hsien-Yuan Lane, of China Medical University, E211 is more effective than a placebo in improving negative schizophrenia symptoms. Although sodium benzoate is usually safe, it may cause mild side effects in certain individuals. … [30] The report's author, Jim Stevenson from Southampton University, said: "The results suggest that consumption of certain mixtures of artificial food colours and sodium benzoate preservative are associated with increases in hyperactive behaviour in children. Results showed significant adverse affects on the children's behaviour with one mix but not another and in older children but less so in the 3 year olds. Dangers of Sodium Benzoate. Benzoic acid is generally not used directly due to its poor water solubility. 5 may cause sever asthma symptoms.2. Also, it is the main ingredient of various paint stripper products, spot removers, and rubber cement, due to its highly solvent and destructive qualities. It is also used as a preservative in medicines and cosmetics. . Sodium benzoate is a substance which has the chemical formula C6H5COONa. acetic acid in vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (acetic acid), condiments, and frozen yogurt toppings. For instance, there will be more than 600,920 cancer deaths and 1,688,780 new cancer cases diagnosed in the United States in 2017. But for many people with food allergies and intolerances, it’s the difference between sickness and health. Cancer has a big impact on society across the world and in the US. One product on the market is called Natamax, a natural antimycotic based on natamycin, produced by fermentation using a string of „Streptomyces natalensis” and blended with lactose. Artificial food additives and the effects they have on our children. Additional severe side effects may result from the combination of sodium phenylacetate and E211, including chest pains, severe headache, fainting, slow heartbeat, blurred vision, unresponsiveness, and slurred speech. [27] Most of the beverages that tested above the limit have been reformulated and subsequently tested below the safety limit. 4.They could contain BHA … The results were inconsistent regarding sodium benzoate, so the FSA recommended further study. It can be produced by reacting sodium hydroxide with benzoic acid. Have you checked lately what your drinks contain in the way of additives and preservatives? Sodium benzoate, along with phenylbutyrate, is used to treat hyperammonemia. Preservative 211 - check what you eat and drink by Vena McGrath. If the intracellular pH falls to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase decreases sharply,[20] which inhibits the growth and survival of microorganisms that cause food spoilage. © Copyright 2021 YOUR HEALTH REMEDY. Sodium benzoate was one of the chemicals used in 19th century industrialised food production that was investigated by Dr. Harvey W. Wiley with his famous 'Poison Squad' as part of the US Department of Agriculture. Any idea how to flush it out your system? We talk about artificial colours in our food and drink and we also talk about preservative 211. In the present day, it is one of the most frequent neurodevelopmental disorders of childhood. Benzoates have a reputation as one of the worst additives that provoke behavioural and learning problems in … [7] Sodium benzoate is also allowed as an animal food additive at up to 0.1%, per the Association of American Feed Control Officials. For some people can also produce mild allergy symptoms, which can include – localized itching, cough, redness, rash, swelling, or congestion. Share Save Follow Me. Nasacort vs Nasonex – Which Is Better To Treat Allergic Rhinitis? It is made by the neutralization of benzoic acid, a substance that is present in numerous products, ranging from cosmetics to food. ADHD (Attention Deficit Hyperactivity Disorder) is a brain-based syndrome that has to do with the regulation of a particular set of brain functions and related behaviors. [12][13][14] Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. Consuming foods and drinks containing this compound may promote various types of cancer, due to the fact that when is combined with ascorbic acid, it transforms in benzene, that according to studies can definitely cause certain types of cancers. Also, this compound is mutagenic, clastogenic, and cytotoxic to human lymphocytes in vitro. "[30], InChI=1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1, InChI=1/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1, Except where otherwise noted, data are given for materials in their, early history of food regulation in the United States, "International Programme on Chemical Safety", "Skin Deep® Cosmetics Database | Environmental Working Group", "Suggested guidelines for the diagnosis and management of urea cycle disorders", Add-on Treatment of Benzoate for Schizophrenia A Randomized, Double-blind, Placebo-Controlled Trial of d-Amino Acid Oxidase Inhibitor, Mental Health Research Institute Staff Publications, "Cinnamon May Help Halt Parkinson's Disease Progression - News Releases - Rush University Medical Center", mayoclinic.org, Caffeine And Sodium Benzoate (Injection Route), ebi.ac.uk, CHEBI:32140 - sodium caffeine benzoate, "Studies on the mechanism of the antifungal action of benzoate", "CFR - Code of Federal Regulations Title 21", "Concise International Chemical Assessment Document 26: Benzoic acid and sodium benzoate", "Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate", "Data on Benzene in Soft Drinks and Other Beverages", United States Food and Drug Administration, Food Standards Agency issues revised advice on certain artificial colours, Agency revises advice on certain artificial colours, The United States Pharmacopeial Convention, International Programme on Chemical Safety - Benzoic Acid and Sodium Benzoate report, "Dose-dependent pharmacokinetics of benzoic acid following oral administration of sodium benzoate to humans", 2008 United States salmonellosis outbreak, 2017–18 South African listeriosis outbreak, 2018 Australian rockmelon listeriosis outbreak, Spanish Agency for Food Safety and Nutrition, https://en.wikipedia.org/w/index.php?title=Sodium_benzoate&oldid=998455787, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 5 January 2021, at 13:16.