DOI: 10.1016/j.molliq.2018.09.076. RHODIACID AA - ADIPIC ACID Revision Date 28.02.2020 PRCO90076334 Version : 3.00 / GB ( EN ) 1 / 37 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier - Trade name RHODIACID AA - ADIPIC ACID - Index-No. Low-cost system based on image analysis to determine solubility curves. This article is cited by Adipic acid is used as precursor in manufacture of nylon. Industrial & Engineering Chemistry Research. Solubility of Adipic Acid in Acetone, Chloroform, and Toluene, Research and Development Center for Petrochemical Technology, Tianjin University, Tianjin 300072, P. R. China. The solubility of adipic acid (1,6-hexanedioic acid) in acetone, chloroform, and toluene has been measured, respectively, at temperatures ranging from (298.15 to 323.15) K and (298.15 to 333.15) K by a static analytical method. It is freely soluble in alcohol, soluble in acetone, and slightly soluble in water. Determination and Correlation of Solubilities for Succinic Acid in the Adipic Acid + Glutaric Acid + Acetone Mixture and Adipic Acid in the Succinic Acid + Glutaric Acid + Acetone Mixture. Adipic Acid occurs as white crystals or a crystalline powder. It is a precursor to diverse industrial products that include polymers, plasticizers, and as a component of many hair and skin conditioners. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism. https://doi.org/10.1016/j.molliq.2019.111735, https://doi.org/10.1016/j.jct.2019.06.033, https://doi.org/10.1016/j.molliq.2018.09.076, https://doi.org/10.1016/j.jct.2014.05.009, https://doi.org/10.1016/j.snb.2012.11.097, https://doi.org/10.1016/j.fluid.2011.01.014. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. An odd–even effect on solubility of dicarboxylic acids in organic solvents. ... (25 deg C, exp database VP ) Water Solubility Estimate from Log Kow (WSKOW v1.41): Water Solubility at 25 deg C (mg/L): 1.673e+005 log Kow used: 0.08 (expkow database) no-melting pt equation used Water Sol (Exper. The key difference between adipic acid and salicylic acid is that adipic acid contains two carboxyl acid groups, whereas salicylic acid contains one carboxyl acid group per molecule.. Adipic acid and salicylic acid are organic compounds. expressed as [adipic acid]water/[adipic acid]ether? use 3 decimal places. The thermodynamic parameters of solution of adipic acid in the above solvents were calculated. Determination of the Adipic Acid Solubility Curve in Acetone by Using ATR-FTIR and Heat Flow Calorimetry. Find more information about Crossref citation counts. It is insoluble in water. Solubility of drug-like molecules in pure organic solvents with the CPA EoS. adipic acid and solubility-very soluble in hot water and almost insoluble in cold water-so water is an ideal solvent for recrystallization of this compound. 355 DEFINITION Chemical names Hexanedioic acid, 1,4-Butanedicarboxylic acid Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. 3 decimal place balance. Weiping Luo, Mengqi Yan, XiaoXiao Sheng, Bao Tao, Sile Shi, Wei Deng, Weijun Yang. It is slightly soluble in water and soluble in alcohol and acetone. It is an emulsifier for Drilling Muds and Fluids as well. Andreia de P. M. da Silva and João F. Cajaiba da Silva . of applications: resins, adhesives, coatings, plastics, paper, plasticizers, detergency . The primary hazard is the threat to the environment. APPEARANCE. A sampler for determination of the temperature dependence of the solubility of solids in liquids by the isothermal method was suggested. The different solubility of adipic acid in various solvents results mainly from the structure and solvent polarity. It has a slight acidic taste and a very faint odor. Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. Weiping Luo, Dong Ruan, Dawei Liu, Kaili Xie, Xiuqing Li, Wei Deng, and Cancheng Guo . Solubilities of Adipic Acid and Succinic Acid in a Glutaric Acid + Acetone or n-Butanol Mixture. You are currently offline. always use the smallest container you can to make measurements and to do experiments. Marcus A. O’Mahony, Denise M. Croker, Åke C. Rasmuson, Stéphane Veesler, and Benjamin K. Hodnett . Adipic acid is also used in baking powders instead of cream of tartar and other foods. High purity Adipic Acid used for the production of nylon 66 and for a wide range . Dongwei Wei, Hui Li, Cheng Liu, and Baohe Wang . Historically, adipic acid was prepared from various fats using oxidation. the Altmetric Attention Score and how the score is calculated. Sile Shi, Mengqi Yan, Bao Tao, Weiping Luo. Adipic acid (AA) CAS-No 124-04-9 . Andreia de P.M. da Silva, Priscilla B. de Oliveira, Thiago B. Bandini, Amaro G. Barreto Junior, Rodrigo C. de Sena, João F. Cajaiba da Silva. USE: Adipic acid is a commercially important chemical used during the production of nylon, plastics, lubricants, adhesives, and polyurethane foam. Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. Mengqi Yan, Xiuqing Li, Bao Tao, Lintao Yang, Weiping Luo. The solubility of adipic acid in water is 1.5 g. per 100 mL at 15?C, and 0.6 g per 100 mL in. Microscale Solubility Measurements of Matrix-Assisted Laser Desorption–Ionization (MALDI) Matrices Using Attenuated Total Reflection (ATR) Fourier Transform Infrared Spectroscopy (FT-IR) Coupled with Partial Least Squares (PLS) Analysis. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Solubility prediction, solvate and cocrystal screening as tools for rational crystal engineering. This carboxylic acid is vital to industry. This organic compound is the most important synthetic dicarboxylic acid produced annually. It is mainly as a precursor for the production of nylon. Some features of the site may not work correctly. Also, it is less soluble in water and is soluble in alcohol and acetone. Ximeng Yu, Zhongquan Shen, Qing Sun, Nianlong Qian, Chao Zhou, and Jizhong Chen . This probably attributes to the incompatible structures. Will likely be mobile in the environment due to its water solubility. The Effect of Temperature on the Solubility of 11-Cyanoundecanoic Acid in Cyclohexane, n-Hexane, and Water. This produces toxic and corrosive fumes of valeric acid and other substances. Get article recommendations from ACS based on references in your Mendeley library. The solubility of adipic acid (1,6-hexanedioic acid) in acetone, chloroform, and toluene has been measured, respectively, at temperatures ranging from (298.15 to 323.15) K and (298.15 to 333.15) K by a static analytical method. Fátima L. Mota, António J. Queimada, Simão P. Pinho, Eugénia A. Macedo. It is used heavily in the production of textiles, particularly nylon. Yanyan Li, Yatao Wang, Zhuoyuan Ning, Jianfang Cui, Qiaoye Wu, and Xunqiu Wang . If not breathing, give artificial respiration. CAS: 124-04-9. ADI 0-5 mg/kg bw, established at the 21st JECFA in 1977. The solubility of adipic acid in methanol, ethanol, propanol, isopropanol, n-butanol, tert-butanol, acetone, 1,4-dioxane, acetic acid, and water was measured within the 0–60°C temperature range. You’ve supercharged your research process with ACS and Mendeley! it is used in powdered drinks, beverages, gelatin desserts, loz- … Adipic acid (butane-1,4-dicarboxylic acid, C6 H 10 O 4) (Figure 27) is a white crystalline powder of C6-straight chain dicarboxylic acid, and is one of the most used chemicals in the world today (Table 1). Adipic acid is present in some plants and is a chemical in tobacco and tobacco smoke. The solubility of adipic acid in methanol, ethanol, propanol, isopropanol, n -butanol, tert -butanol, acetone, 1,4-dioxane, acetic acid, and water was measured within the 0–60°C temperature range. Adipic Acid >99 124-04-9 204-673-3 C 6 H 10 O 4 146.14 g/mol 4. Mobility. Function: Buffer; neutralizing agent. The solubility of adipic acid in cyclohexanol and cyclohexanone is lower than that in acetic acid. Adipic Acid is an acidulant and flavoring agent. White crystalline powder. Adipic acid EC50= 31.3 mg/L 72h EC50 = 26.6 mg/L 96h Leuciscus idus: LC50 = 230 mg/L 96h EC50 = 91.9 mg/L 17 hEC50 = 85.7 mg/L 48h Persistence and DegradabilityPersistence is unlikely Bioaccumulation/ AccumulationNo information available. From an industrial perspective, it is the most important dicarboxylic acid: about 2.5 billion kilograms of this white crystalline powder are produced annually, mainly as a precursor for the production of nylon. Measurement and Correlation for Solubilities of Adipic Acid in Acetic Acid + ε-Caprolactone Mixtures and Cyclohexanone + ε-Caprolactone Mixtures. An 84% conversion of adipic acid's carbon content to carbon dioxide was observed after 30 days aerobic incubation in soil biometer flasks at Decomposes on heating. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Journal of Molecular Liquids 2018, 272, 106-119. Sign in to download full-size image Figure 27. Formula: C 6 H 1 0 O 4 / HOOC(CH 2) 4 COOH Molecular mass: 146.14 Boiling point: 338°C Melting point: 152°C Density: 1.36 g/cm³ Solubility in water, g/100ml at 15°C: 1.4 (moderate) Solubility of succinic acid, glutaric acid and adipic acid in propionic acid + ε-caprolactone mixtures and propionic acid + cyclohexanone mixtures: Experimental measurement and thermodynamic modeling. Get medical attention. Other patented processes include those using phenolas feedst… The substance is a weak acid. ADIPIC ACID Prepared at the 53rd JECFA (1999) and published in FNP 52 Add 7 (1999), superseding specifications prepared at the 19th JECFA (1975), published in NMRS 55B (1976) and in FNP 52 (1992). Adipic Acid. Librarians & Account Managers. COMPOSITION. Find more information on the Altmetric Attention Score and how the score is calculated. Current commercial adipic acid is produced from cyclohexaneby two oxidation steps. & Account Managers, For Environmental: Adipic acid is not expected to volatilize from dry soil surfaces based on its extrapolated vapor pressure. Reviewers, Librarians Adipic acid otherwise rarely occurs in nature, but it is known as manufactured E number food additive E355. Weiping Luo, Xiuqing Li, Dong Ruan, Dawei Liu, Kaili Xie, Jing Wang, Wei Deng, Qiang Liu, and Zhaoke Chen . Reacts with oxidizing materials. it has a ph of 2.86 at 0.6% usage level at 25°c. It is not hygroscopic. They contain carboxylic groups as their functional group.However, they have different chemical and physical properties as well as different applications. What is the Kd of adipic acid. Azelaic acid is an organic compound found in wheat, rye, and barley. Remember the Kd is usually the ratio of. Adipic acid is an aliphatic dicarboxylic acid with the formula (CH2)4 (COOH)2. PRODUCT DESCRIPTION. adipic acid tableting tablet lubricant composition Prior art date 1969-07-07 Legal status (The legal status is an assumption and is not a legal conclusion. Adipic Acid also known as Hexane-1,6-dioic acid is a dibasic acid with the molecular formula C 3 H 8 O 4, CAS 124-04-9.Adipic acid is slightly soluble in water and soluble in alcohol and acetone. The dependence of the solubility on the solvent and temperature was…, Solubility of Adipic Acid in Acetone, Chloroform, and Toluene, Investigation on solubility of hydroxy dibasic acids in alkanolamine solutions, Solubilities of Adipic Acid and Succinic Acid in a Glutaric Acid + Acetone or n-Butanol Mixture, Determination of the Adipic Acid Solubility Curve in Acetone by Using ATR-FTIR and Heat Flow Calorimetry, Solubility and thermodynamics of vitamin C in binary liquid mixtures involving water, methanol, ethanol and isopropanol at different temperatures, Thermodynamics of cis,cis-muconic acid solubility in various polar solvents at low temperature range, Measurement and Correlation of the Solubility for 4,4′-Diaminodiphenylmethane in Different Solvents, KINETICS AND MECHANISM OF OXIDATION OF MIXTURE OF OXALIC ACID AND ADIPIC ACID BY CHROMIC ACID IN PRESENCE OF ACETIC ACID, Measurement and Correlation for Solubilities of Adipic Acid, Glutaric Acid, and Succinic Acid in Dimethyl Adipate + Methanol Mixtures, Measurement and Correlation for Solubilities of Adipic Acid, Glutaric Acid and Succinic Acid in Acetic Acid + Cyclohexanone Mixtures, The solubilities of dicarboxylic acids in benzene and aqueous solutions, By clicking accept or continuing to use the site, you agree to the terms outlined in our. Conventionally it was manufactured from petrochemicals but in recent days it can be synthesized from renewable substrates by means of biological methods. Solubility of succinic acid, glutaric acid and adipic acid in propionic acid + ε-caprolactone mixtures and propionic acid + cyclohexanone mixtures: Experimental measurement and thermodynamic modeling. A sampler for determination of the temperature dependence of the solubility of solids in liquids by the isothermal method was suggested. Expired - Lifetime Application number Inventor George Carr Hoss b. it is characterized as stable, nonhygroscopic, and slightly soluble, with a water solubility of 1.9 g/100 ml at 20°c. Adipic Acid × × Purity: >99.0%(GC ... Solubility in Methanol: almost transparency: Properties (reference) Melting Point: 153 °C: Solubility in water: Slightly soluble: Degree of solubility in water : 22 g/l 20 °C: Solubility (very soluble in) Alcohol: Solubility (soluble in) If breathing is difficult, give oxygen. Cyclohexane + O2 → cyclohexanol and cyclohexanone 2. cyclohexanol/cyclohexanone + nitric acid+ air → adipic acid + nitrous oxide (The mixture of cyclohexanol and cyclohexanone produced from cyclohexane is commercially called "KA oil", the abbreviation of "Ketone-Alcohol oil".) CAS Number: 124-04-9 Formula Weight: 146.14 Formula: HO 2 C(CH 2 ) 4 CO 2 H Density (g/mL): 1.34 Boiling Point (°C): 377 Freezing Point (°C): 152 Solubility: Acetone and Alcohol Synonyms: Hexanedioic Acid Shelf Life (months): 12 Storage: GreenChemicals for science education are available in easy-to-use formats with instructions for students to be introduced to a variety of subjects. Adipic Acid Chemical Structure Composition. Adipic acid is a white crystalline solid. The compositions of the adipic acid in saturated solution were analyzed by acid−base titration. Biodegradability screening tests indicate that adipic acid is readily biodegradable. SYNONYMS INS No. It is very soluble in water. Adipic Acid TCC’s Adipic Acid is a mildly toxic, white, crystalline compound. You have to login with your ACS ID befor you can login with your Mendeley account. Solubilities of Adipic Acid, Glutaric Acid, and Succinic Acid in Dimethyl Glutarate + Methanol Mixtures: Experimental Measurement and Thermodynamic Modeling. Solubility of succinic acid, glutaric acid and adipic acid in propionic acid + ε-caprolactone + water mixtures: Experimental measurement and thermodynamic modeling. 18 publications. These metrics are regularly updated to reflect usage leading up to the last few days. Adipic acid is a straight-chain aliphatic dicarboxylic acid, commonly used in the manufacturing of nylon-6,6 and plasticizers. A Unified Thermodynamics Model for Solid–Liquid Equilibrium, Liquid–Liquid Equilibrium, and Vapor–Liquid Equilibrium of Cyclohexane Oxidation Systems: NRTL Model. Malonic acid (IUPAC systematic name: propanedioic acid) is a dicarboxylic acid with structure CH 2 (COOH) 2.The ionized form of malonic acid, as well as its esters and salts, are known as malonates.For example, diethyl malonate is malonic acid's diethyl ester.The name originates from the Greek word μᾶλον (malon) meaning 'apple'. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. Nearly all commercial adipic acid is produced from cyclohexane. Please reconnect, Authors & Measurement and correlation for solubilities of succinic acid, glutaric acid and adipic acid in five organic solvents. The production of nylon comes from a reaction with hexamethylene diamine, also supplied by Parchem.. Adipic acid can also be found in the production of foods as a flavoring agent to add tartness.. 151-152 °C (for adipic acid) EU Food Improvement Agents 3.2.3 Solubility Approximately 50 g/100 ml water (20 °C) 607-144-00-9 - REACH : Registration number 01-2119457561-38-0009 Bo Chen, Mengqi Yan, Bao Tao, Lintao Yang. TECHNICAL DATA. It is a white, crystalline compound with a slight acid taste and very faint odor. The non-toxic saturated dicarboxylic acid is produced as a white powder. Measuring the Solubility of a Quickly Transforming Metastable Polymorph of Carbamazepine. ether at the same temperature. Adipic Acid. Adipic acid [ACD/IUPAC Name] [Wiki] Adipinsäure [German] [ACD/IUPAC Name] Asapic. Solubilities of Adipic Acid in Cyclohexanol + Cyclohexanone Mixtures and Cyclohexanone + Cyclohexane Mixtures. Calculate the fraction of adipic acid that. Its solubility is very low in water and soluble in organic solvents like alcohol and acetone. Find more information about Crossref citation counts. Hui Zhang, Qiuxiang Yin, Zengkun Liu, Junbo Gong, Ying Bao, Meijing Zhang, Hongxun Hao, Baohong Hou, Chuang Xie. Valeric acid and other substances was used to correlate the Experimental data CH2 ) 4 COOH! Expected to volatilize from dry soil surfaces based on its extrapolated vapor pressure to limit spread... How the Score is a mildly toxic, white, crystalline compound with a water solubility, white crystalline... Equilibrium, and Benjamin K. Hodnett: adipic acid is an emulsifier for Drilling Muds and Fluids well. For solubilities of adipic acid is an ideal solvent for recrystallization of this compound Mahony, Denise M. Croker Åke! Rye, and Succinic acid in Cyclohexane, n-Hexane, and Xunqiu Wang is used in! Acid otherwise rarely occurs in nature, but it is freely soluble in water and soluble. Known as manufactured E number food additive E355 cyclohexanol and Cyclohexanone + Cyclohexane Mixtures a of! 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At 0.6 % usage level at 25°c Experimental measurement and Correlation for solubilities of Succinic acid, Glutaric and... Was prepared from various fats using oxidation the manufacturing of nylon-6,6 and plasticizers Shi, Mengqi Yan Bao... And water Cajaiba da Silva biodegradability screening tests indicate that adipic acid was from! By the isothermal method was suggested Librarians & Account Managers, for Librarians & Account Managers 2018!, 1,4-Butanedicarboxylic acid adipic acid and Succinic acid, commonly used in baking instead! Deng, Weijun Yang Quickly Transforming Metastable Polymorph of Carbamazepine ACS and Mendeley recrystallization of compound! By means of biological methods the compositions of the temperature dependence of status.